Professor Raven's Recent Publications
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Gumiero, A.; Metcalfe, C. L.; Pearson, A. R.; Raven, E. L.; Moody, P. C. E. J. Biol. Chem. 2011, 286, 1260-1268. ‘The nature of the ferryl heme in Compounds I and II.’
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Gumiero, A.; Murphy, E. J.; Metcalfe, C. L.; Moody, P. C. E.; Raven, E. L. Arch. Biochem. Biophys. 2010, 500, 13-20. Special issue of peroxidase chemistry. ‘An analysis of substrate binding interactions in the heme peroxidase enzymes: a structural perspective.’
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Davydov, R.; Chauhan, N.; Thackray, S. J.; Anderson, J. L.; Papadopoulou, N.; Mowat, C.; Chapman, S. K.; Raven, E. L.; Hoffman, B. M. J. Amer. Chem. Soc., 2010, 132, 5494-5500.
‘Probing the ternary complexes of indoleamine and tryptophan 2,3-dioxygenases by cryoreduction EPR and ENDOR spectroscopy.’ -
Raven, E. L.; Robinson, N., Nat. Prod. Rep., 2010, 27, 635-636. Metals in cells themed issue.
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Ortiz de Montellano, P. M.; Raven, E. L., Nat. Prod. Rep. 2007, 24, 499. The chemistry and biochemistry of heme proteins. .
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Pipirou, Z.; Bottrill, A. R.; Metcalfe, C. M.; Mistry, S. C.; Badyal, S. K.; Rawlings, B. J.; Raven, E. L. Biochemistry 2007, 46, 2174-2180. ‘Autocatalytic Formation of a Covalent Link between Tryptophan 41 and the Heme in Ascorbate Peroxidase.’
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Efimov, I.; Papadopoulou, N. D.; McLean, K. J.; Badyal, S. K.; Macdonald, I. K.; Munro, A. W.; Moody, P. C. E.; Raven, E. L. Biochemistry 2007, 46, 8017-8023. ‘The Redox Properties of Ascorbate Peroxidase.’
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Metcalfe, C. L.; Daltrop, O.; Ferguson, S. J.; Raven, E. L. Biochem. J. 2007, 408, 355-361. ‘Tuning the formation of a covalent heme-protein link by selection of reductive or oxidative conditions as exemplified by ascorbate peroxidase.’
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Pipirou, Z.; Bottrill, A. R.; Svistunenko, D. A.; Efimov, I.; Basran, J.; Mistry, S. C.; Cooper, C. E.; Raven, E. L. Biochemistry 2007, 46, 13269-13278. ’The reactivity of heme in biological systems: autocatalytic formation of both tyrosine-heme and tryptophan-heme covalent links in a single protein architecture.’
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Metcalfe, C. L.; Macdonald, I. K.; Murphy, E. J.; Brown, K. A.; Raven, E. L.; Moody, P. C. E. J. Biol. Chem. 2008, J. Biol. Chem. 283, 6193-6200. ‘The tuberculosis prodrug isoniazid bound to activating peroxidases.’
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Badyal, S. K.; Metcalfe, C. L.; Basran, J.; Efimov, I.; Moody, P. C. E.; Raven, E. L. Biochemistry 2008, 47, 4403-4409. ‘Iron oxidation state as a molecular trigger controlling active site structure in a heme peroxidase.’
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Chauhan, N.; Basran, J.; Efimov, I.; Svistunenko, D. A.; Seward, H. E.; Peter C. E. Moody, Raven, E. L. Biochemistry 2008, 47, 4752-4760. Back to back with below. ‘The role of serine 167 in human indoleamine 2,3-dioxygenase: a comparison with tryptophan 2,3-dioxygenase.’
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Basran, J.; Rafice, S.; Chauhan, N.; Efimov, I.; Cheesman, M. R.; Ghamsari, L.; Raven, E. L. Biochemistry 2008, 47, 4761-4769. Back to back with above. ‘A kinetic, spectroscopic and redox study of human tryptophan 2,3, dioxygenase.’
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Murphy, E. J.; Metcalfe, C. L.; Basran, J.; Moody, P. C. E.; Raven, E. L. Biochemistry 2008, 47, 13933-13941.
‘Engineering the substrate specificity and reactivity of a heme protein: creation of an ascorbate binding site in cytochrome c peroxidase’. -
Chauhan, N.; Thackray, S. J.; Rafice, S. A.; Eaton, G.; Lee, M.; Efimov, I.; Basran, J.; Jenkins, P. R.; Mowat, C. G.; Chapman, S. K.; Raven, E. L. J. Amer. Chem. Soc., 2009, 131, 4186-4187.
‘Reassessment of the Reaction Mechanism in the Heme Dioxygenases.’ -
Pipirou, Z.; Guallar, V.; Basran, J.; Metcalfe, C. L.; Murphy, E. J.; Bottrill, A. R.; Mistry, S. C.; Raven, E. L. Biochemistry, 2009, 48, 3593-3599.
‘Peroxide-dependent Formation of a Covalent Link between Trp51 and the Heme in Cytochrome c Peroxidase.’ -
Badyal, S. K.; Eaton, G.; Mistry, S.; Pipirou, Z.; Basran, J.; Metcalfe, C. L.; Gumiero, A.; Handa, S.; Moody, P. C. E.; Raven, E. L. Biochemistry 2009, 48, 4738-4746.
‘Evidence for Heme Oxygenase Activity in a Heme Peroxidase’.
