Publications 2011
Agarwal S, Banerjee J, Baker R, Conroy S, Hsu R, Rashid A, Camosso-Stefinovic J, Sinfield P, Habiba M. Potentially avoidable emergency department attendance: interview study of patients' reasons for attendance. Emerg Med J. 2011 Dec 28 Epub
Yates T, Davies MJ, Schwarz PE, Khunti K. Diabetes prevention: A call to action. Indian J Med Res. 2011 Nov 134 5 579-82
Salvi E et al (including Samani NJ). Genomewide Association Study Using a High-Density Single Nucleotide Polymorphism Array and Case-Control Design Identifies a Novel Essential Hypertension Susceptibility Locus in the Promoter Region of Endothelial NO Synthase. Hypertension. 2011 Dec 19 Epub
Herder C, Peeters W, Illig T, Baumert J, de Kleijn DP, Moll FL, Poschen U, Klopp N, Müller-Nurasyid M, Roden M, Preuss M; CARDIoGRAM Consortium, Karakas M, Meisinger C, Thorand B, Pasterkamp G, Koenig W, Assimes TL, Deloukas P, Erdmann J, Holm H, Kathiresan S, König IR, McPherson R, Reilly MP, Roberts R, Samani NJ, Schunkert H, Stewart AF. RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies. PLoS One. 2011 6 12 e25734
Filippi M, Rocca MA, De Stefano N, Enzinger C, Fisher E, Horsfield MA, Inglese M, Pelletier D, Comi G. Magnetic resonance techniques in multiple sclerosis: the present and the future. Arch Neurol. 2011 Dec 68 12 1514-20
Petersen AK, Stark K, Musameh MD, Nelson CP, Römisch-Margl W, Kremer W, Raffler J, Krug S, Skurk T, Rist MJ, Daniel H, Hauner H, Adamski J, Tomaszewski M, Döring A, Peters A, Wichmann HE, Kaess BM, Kalbitzer HR, Huber F, Pfahlert V, Samani NJ, Kronenberg F, Dieplinger H, Illig T, Hengstenberg C, Suhre K, Gieger C, Kastenmüller G. Genetic Associations with Lipoprotein Subfractions Provide Information on their Biological Nature. Hum Mol Genet. 2011 Dec 8 Epub
Wilmot EG, Davies MJ, Edwardson CL, Gorely T, Khunti K, Nimmo M, Yates T, Biddle SJ. Rationale and Study Design for a Randomised Controlled Trial to Reduce Sedentary Time in Adults at Risk of Type 2 Diabetes Mellitus: Project STAND (Sedentary Time ANd Diabetes). BMC Public Health. 2011 Dec 8 11 1 908
Crasto W, Khunti K, Davies MJ. An update on exenatide, a novel therapeutic option for patients with type 2 diabetes. Drugs Today (Barc). 2011 Nov 47 11 839-56
Rotival M, Zeller T, Wild PS, Maouche S, Szymczak S, Schillert A, Castagné R, Deiseroth A, Proust C, Brocheton J, Godefroy T, Perret C, Germain M, Eleftheriadis M, Sinning CR, Schnabel RB, Lubos E, Lackner KJ, Rossmann H, Münzel T, Rendon A, Consortium C, Erdmann J, Deloukas P, Hengstenberg C, Diemert P, Montalescot G, Ouwehand WH, Samani NJ, Schunkert H, Tregouet DA, Ziegler A, Goodall AH, Cambien F, Tiret L, Blankenberg S. Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans. PLoS Genet. 2011 Dec 7 12 e1002367
Gieger C et al (including Goodall AH and Samani NJ). New gene functions in megakaryopoiesis and platelet formation. Nature. 2011 Nov 30 480 7376 201-8
Koskela J, Kähönen M, Nieminen T, Lehtinen R, Viik J, Nikus K, Niemelä K, Kööbi T, Tobin MD, Samani NJ, Turjanmaa V, Pörsti I, Lehtimäki T. Allelic variant of NOS1AP effects on cardiac alternans of repolarization during exercise testing. Scand J Clin Lab Invest. 2011 Dec 1 Epub
Nicolaou G, Goodall AH, Erridge C. Diverse Bacteria Promote Macrophage Foam Cell Formation Via Toll-Like Receptor-Dependent Lipid Body Biosynthesis. J Atheroscler Thromb. 2011 Nov 26 Epub
Bhandari SS, Davies JE, Struck J, Ng LL. The diagnostic performance of mid-regional portion of pro-atrial natriuretic peptide for the detection of left ventricular hypertrophy in Caucasian hypertensive patients. J Hum Hypertens. 2011 Nov 24 Epub
Roland D, Clarke C, Borland M, Pascoe E. Adequately assessing dehydration: A holy grail of paediatric emergency medicine. Int J Emerg Med. 2011 Nov 24 4 71
Nielsen JC, Thomsen PE, Højberg S, Møller M, Riahi S, Dalsgaard D, Mortensen LS, Nielsen T, Asklund M, Friis EV, Christensen PD, Simonsen EH, Eriksen UH, Jensen GV, Svendsen JH, Toff WD, Healey JS, Andersen HR; on behalf of the DANPACE investigators. Atrial fibrillation in patients with sick sinus syndrome: the association with PQ-interval and percentage of ventricular pacing. Europace. 2011 Nov 20 Epub
Singh H, Tahir TA, Alawo DO, Issa E, Brindle NP. Molecular control of angiopoietin signalling. Biochem Soc Trans. 2011 Dec 1 39 6 1592-6
Johnson T et (including Tomaszewski M and Goodall AH); The Cardiogenics Consortium; The Global BPgen Consortium (including Braund PS, Nelson CP, Tobin MD and Samani NJ). Blood Pressure Loci Identified with a Gene-Centric Array. Am J Hum Genet. 2011 Dec 9 89 6 688-700
Fogl C, Puckey L, Hinssen U, Zaleska M, El-Mezgueldi M, Croasdale R, Bowman A, Matsukawa A, Samani NJ, Savva R, Pfuhl M. A structural and functional dissection of the cardiac stress response factor MS1. Proteins. 2011 Sep 19 Epub
Aw D, Hayhoe B, Smajdor A, Bowker LK, Conroy SP, Myint PK. Advance care planning and the older patient. QJM. 2011 Nov 10 Epub
Bown MJ, Jones GT, Harrison SC, Wright BJ, Bumpstead S, Baas AF, Gretarsdottir S, Badger SA, Bradley DT, Burnand K, Child AH, Clough RE, Cockerill G, Hafez H, Julian A Scott D, Futers S, Johnson A, Sohrabi S, Smith A, Thompson MM, van Bockxmeer FM, Waltham M, Matthiasson SE, Thorleifsson G, Thorsteinsdottir U, Blankensteijn JD, Teijink JA, Wijmenga C, de Graaf J, Kiemeney LA, Assimes TL, McPherson R; CARDIoGRAM Consortium; Global BPgen Consortium; DIAGRAM Consortium; VRCNZ Consortium, Folkersen L, Franco-Cereceda A, Palmen J, Smith AJ, Sylvius N, Wild JB, Refstrup M, Edkins S, Gwilliam R, Hunt SE, Potter S, Lindholt JS, Frikke-Schmidt R, Tybjærg-Hansen A, Hughes AE, Golledge J, Norman PE, van Rij A, Powell JT, Eriksson P, Stefansson K, Thompson JR, Humphries SE, Sayers RD, Deloukas P, Samani NJ. Abdominal Aortic Aneurysm Is Associated with a Variant in Low-Density Lipoprotein Receptor-Related Protein 1. Am J Hum Genet. 2011 Nov 11 89 5 619-27
Marques FZ, Campain AE, Tomaszewski M, Zukowska-Szczechowska E, Yang YH, Charchar FJ, Morris BJ. Gene Expression Profiling Reveals Renin mRNA Overexpression in Human Hypertensive Kidneys and a Role for MicroRNAs. Hypertension. 2011 Dec 58 6 1093-8
Armaganijan LV, Toff WD, Nielsen JC, Andersen HR, Connolly SJ, Ellenbogen KA, Healey JS. Are Elderly Patients at Increased Risk of Complications Following Pacemaker Implantation? A Meta-Analysis of Randomized Trials. Pacing Clin Electrophysiol. 2011 Oct 31 Epub
Gray LJ, Yates T, Davies MJ, Brady E, Webb DR, Sattar N, Khunti K. Defining obesity cut-off points for migrant South asians. PLoS One. 2011 6 10 e26464
Heid IM et at (including Samani NJ). Corrigendum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet. 2011 Oct 27 43 11 1164
Moat NE, Ludman P, Belder MA, Bridgewater B, Cunningham AD, Young CP, Thomas M, Kovac J, Spyt T, Maccarthy PA, Wendler O, Hildick-Smith D, Davies SW, Trivedi U, Blackman DJ, Levy RD, Brecker SJ, Baumbach A, Daniel T, Gray H, Mullen MJ. Long-Term Outcomes After Transcatheter Aortic Valve Implantation in High-Risk Patients With Severe Aortic Stenosis The U.K. TAVI (United Kingdom Transcatheter Aortic Valve Implantation) Registry. J Am Coll Cardiol. 2011 Nov 8 58 20 2130-8
Büsst CJ, Bloomer LD, Scurrah KJ, Ellis JA, Barnes TA, Charchar FJ, Braund P, Hopkins PN, Samani NJ, Hunt SC, Tomaszewski M, Harrap SB. The Epithelial Sodium Channel {gamma}-Subunit Gene and Blood Pressure: Family Based Association, Renal Gene Expression, and Physiological Analyses. Hypertension. 2011 Dec 58 6 1073-8
Naylor AR. A Surgeon's View on Endarterectomy and Stenting in 2011: Lest We Forget, It's All About Preventing Stroke. Cardiovasc Intervent Radiol. 2011 Oct 18 Epub
Huq R, Philbey CE, Mistri AK, Panerai RB, Robinson TG. Dynamic cerebral autoregulation assessed by respiratory manoeuvres in non-insulin-treated Type 2 diabetes mellitus. Diabet Med. 2011 Oct 17
Ringdal KG, Lossius HM, Jones JM, Lauritsen JM, Coats TJ, Palmer CS, Lefering R, Di Bartolomeo S, Dries DJ, Soreide K, Collaborators TU. Collecting core data in severely injured patients using a consensus trauma template: an international multicentre study. Crit Care. 2011 Oct 12 15 5 R237
Naylor AR. Time to rethink management strategies in asymptomatic carotid artery disease. Nat Rev Cardiol. 2011 Oct 11 Epub
Khunti K, Taub N, Webb D, Srinivasan B, Stockman J, Griffin SJ, Simmons RK, Davies MJ. Validity of self-assessed waist circumference in a multi-ethnic UK population. Diabet Med. 2011 Oct 11 Epub
Sett AK, Robinson TG, Mistri AK. Current status of statin therapy for stroke prevention. Expert Rev Cardiovasc Ther. 2011 Oct 9 10 1305-14
Williams B, Lacy P, Yan P, Chua NH, Liang C, Ting CM. Reply. J Am Coll Cardiol. 2011 Oct 11 58 16 1731-2
Antony R, Daghem M, McCann GP, Daghem S, Moon J, Pennell DJ, Neubauer S, Dargie HJ, Berry C, Payne J, Petrie MC, Hawkins NM. Cardiovascular magnetic resonance activity in the United Kingdom: a survey on behalf of the british society of cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2011 Oct 6 13 57
Noah MA, Peek GJ, Finney SJ, Griffiths MJ, Harrison DA, Grieve R, Sadique MZ, Sekhon JS, McAuley DF, Firmin RK, Harvey C, Cordingley JJ, Price S, Vuylsteke A, Jenkins DP, Noble DW, Bloomfield R, Walsh TS, Perkins GD, Menon D, Taylor BL, Rowan KM. Referral to an extracorporeal membrane oxygenation center and mortality among patients with severe 2009 influenza A(H1N1). JAMA. 2011 Oct 19 306 15 1659-68
Conroy SP. Screening for falls may not be cost effective. (letter) BMJ. 2011 Oct 4 343
Cock HR; ESETT Group. Inc Coats TJ. Established status epilepticus treatment trial (ESETT). Epilepsia. 2011 Oct 52 Suppl 8 50-2
IBC 50K CAD Consortium. Inc Barnes T, Rafelt S, Codd V, Tomaszewski M, Braund P, Thompson JR, Samani NJ, Kaiser M, Nelson CP, Goodall AH, Gracey J, Krishnan U, Moore JS, Pollard H. Large-scale gene-centric analysis identifies novel variants for coronary artery disease. PLoS Genet. 2011 Sep 7 9 e1002260
Burton JO, Gray LJ, Webb DR, Davies MJ, Khunti K, Crasto W, Carr SJ, Brunskill NJ. Association of anthropometric obesity measures with chronic kidney disease risk in a non-diabetic patient population. Nephrol Dial Transplant. 2011 Sep 29 Epub
Shah S, Nelson CP, Gaunt TR, van der Harst P, Barnes T, Braund PS, Lawlor DA, Casas JP, Padmanabhan S, Drenos F, Kivimaki M, Talmud PJ, Humphries SE, Whittaker J, Morris RW, Whincup PH, Dominiczak A, Munroe PB, Johnson T, Goodall AH, Cambien F, Diemert P, Hengstenberg C, Ouwehand WH, Felix JF, Glazer NL, Tomaszewski M, Burton PR, Tobin MD, van Veldhuisen DJ, de Boer RA, Navis G, van Gilst WH, Mayosi BM, Thompson JR, Kumari M, Macfarlane PW, Day IN, Hingorani AD, Samani NJ. Four Genetic Loci Influencing Electrocardiographic Indices of Left Ventricular Hypertrophy. Circ Cardiovasc Genet. 2011 Dec 1 4 6 626-635
Ahmad A, Salinet JL Jr, Brown P, Tuan JH, Stafford P, Ng GA, Schlindwein FS. QRS subtraction for atrial electrograms: flat, linear and spline interpolations. Med Biol Eng Comput. 2011 Nov 49 11 1321-8
Maznyczka A, Myat A, Gershlick A. Discontinuation of metformin in the setting of coronary angiography: clinical uncertainty amongst physicians reflecting a poor evidence base. EuroIntervention. 2011 Dec 30 7 9 1103-10
Thomas MG, Kumar A, Thompson JR, Proudlock FA, Straatman K, Gottlob I. (letter) Is high-resolution spectral domain optical coherence tomography reliable in nystagmus? Br J Ophthalmol. 2011 Sep 27
Proudlock F, Gottlob I. Foveal development and nystagmus. Ann N Y Acad Sci. 2011 Sep 1233 292-7
Vorwerk C, Coats TJ. The prognostic value of tissue oxygen saturation in emergency department patients with severe sepsis or septic shock. Emerg Med J. 2011 Sep 21 Epub
Hildick-Smith D, Redwood S, Mullen M, Thomas M, Kovac J, Brecker S, Trivedi U, Young C, Hutchinson N, Maccarthy P, Prendergast B, De Belder M, Monaghan M, Blackman D, Baumbach A, Manoharan G, Moat N. Complications of transcatheter aortic valve implantation: avoidance and management. EuroIntervention. 2011 Sep 7 5 621-8
Verheye S, Ramcharitar S, Grube E, Schofer JJ, Witzenbichler B, Kovac J, Hauptmann KE, Agostoni P, Wiemer M, Lefèvre T, Spaargaren R, Serruys PW, García-García HM, van Geuns RJ. Six-month clinical and angiographic results of the STENTYS® self-apposing stent in bifurcation lesions. EuroIntervention. 2011 Sep 7 5 580-7
Ricketts SL, Rensing KL, Holly JM, Chen L, Young EH, Luben R, Ashford S, Song K, Yuan X, Dehghan A, Wright BJ, Waterworth DM, Mooser V; GEMS Investigators, Waeber G, Vollenweider P, Epstein SE, Burnett MS, Devaney JM, Hakonarson HH, Rader DJ, Reilly MP, Danesh J, Thompson SG, Dunning AM, van Duijn CM, Samani NJ, McPherson R, Wareham NJ, Khaw KT, Boekholdt SM, Sandhu MS. Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease. Int J Mol Epidemiol Genet. 2011 Aug 30 2 3 261-85
Webb DR, Khunti K, Gray LJ, Srinivasan BT, Farooqi A, Wareham N, Griffin SC, Davies MJ; for the ADDITION-Leicester study group. Intensive multifactorial intervention improves modelled 5-year coronary heart disease risk in screen-detected Type 2 diabetes mellitus: a cluster randomized controlled trial. Diabet Med. 2011 Sep 13 Epub
The International Consortium for Blood Pressure Genome-Wide Association Studies (including Tobin MD, Braund PS, Tomaszewski M, Samani NJ). Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011 Sep 11 478 7367 103-109
Wain LV et al (including Nelson CP); LifeLines Cohort Study; AortaGen Consortium; CHARGE Consortium Heart Failure Working Group; KidneyGen consortium; CKDGen consortium; Cardiogenics consortium; CardioGram (including Samani NJ and Tobin MD). Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet. 2011 Sep 11 43 10 1005-11
Karkos CD, Sutton AJ, Bown MJ, Sayers RD. A Meta-analysis and Metaregression Analysis of Factors Influencing Mortality after Endovascular Repair of Ruptured Abdominal Aortic Aneurysms. Eur J Vasc Endovasc Surg. 2011 Dec 42 6 775-86
Peacock WF, Nowak R, Christenson R, Disomma S, Neath SX, Hartmann O, Mueller C, Ponikowski P, Möckel M, Hogan C, Wu AH, Richards M, Filippatos GS, Anand I, Ng LL, Daniels LB, Morgenthaler N, Anker SD, Maisel AS. Short-term Mortality Risk in Emergency Department Acute Heart Failure. Acad Emerg Med. 2011 Sep 18 9 947-958
Suhre K et al; CARDIoGRAM (including Samani NJ). Human metabolic individuality in biomedical and pharmaceutical research. Nature. 2011 Aug 31 477 7362 54-60
Strawbridge RJ et al; DIAGRAM Consortium; GIANT Consortium; MuTHER Consortium; CARDIoGRAM Consortium; C4D Consortium (Including Barnes T, Braund P, Codd V, Goodall AH, Kaiser M, Nelson CP, Samani NJ, Thompson JR, Tomaszewski M). Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes. 2011 Oct 60 10 2624-34
Mehta RL, Davies MJ, Ali S, Taub NA, Stone MA, Baker R, McNally PG, Lawrence IG, Khunti K. Association of cardiac and non-cardiac chronic disease comorbidity on glycaemic control in a multi-ethnic population with type 1 and type 2 diabetes. Postgrad Med J. 2011 Nov 87 1033 763-8
Krause T, Lovibond K, Caulfield M, McCormack T, Williams B; on behalf of the Guideline Development Group. Management of hypertension: summary of NICE guidance. BMJ. 2011 Aug 25 343 d4891
Lovibond K, Jowett S, Barton P, Caulfield M, Heneghan C, Hobbs FR, Hodgkinson J, Mant J, Martin U, Williams B, Wonderling D, McManus RJ. Cost-effectiveness of options for the diagnosis of high blood pressure in primary care: a modelling study. Lancet. 2011 Oct 1 378 9798 1219-30
Maisel A, Mueller C, Nowak RM, Peacock WF, Ponikowski P, Mockel M, Hogan C, Wu AH, Richards M, Clopton P, Filippatos GS, Di Somma S, Anand I, Ng LL, Daniels LB, Neath SX, Christenson R, Potocki M, McCord J, Hartmann O, Morgenthaler NG, Anker SD. Midregion Prohormone Adrenomedullin and Prognosis in Patients Presenting With Acute Dyspnea Results From the BACH (Biomarkers in Acute Heart Failure) Trial. J Am Coll Cardiol. 2011 Aug 30 58 10 1057-67
Edmans J, Conroy S, Harwood R, Lewis S, Elliott RA, Logan P, Bradshaw L, Franklin M, Gladman J. Acute medical unit comprehensive geriatric assessment intervention study (AMIGOS). Trials. 2011 Aug 24 12 200
Thomas MG, Gottlob I, McLean RJ, Maconachie G, Kumar A, Proudlock FA. Reading Strategies in Infantile Nystagmus Syndrome. Invest Ophthalmol Vis Sci. 2011 Oct 17 52 11 8156-65
Ecimovic P, Murray D, Doran P, McDonald J, Lambert DG, Buggy DJ. Direct effect of morphine on breast cancer cell function in vitro: role of the NET1 gene. Br J Anaesth. 2011 Dec 107 6 916-23
London NJ, Srinivasan R, Naylor AR, Hartshorne T, Ratliff DA, Bell PR, Bolia A. Reprinted Article "Subintimal Angioplasty of Femoropopliteal Artery Occlusions: The Long-term Results". Eur J Vasc Endovasc Surg. 2011 Sep 42 Suppl 1 S9-S15
Naylor AR, Mehta Z, Rothwell PM, Bell PR. Reprinted article "Carotid artery disease and stroke during coronary artery bypass: a critical review of the literature". Eur J Vasc Endovasc Surg. 2011 Sep 42 Suppl 1 S73-83
Sayers RD. Commentary. Realistic expectations for patients with stent-graft treatment of abdominal aortic aneurysms. Results of a European multicentre registry. Eur J Vasc Endovasc Surg. 2011 Sep 42 Suppl 1 S72
Ricco JB, Naylor AR. Looking towards the next 25 years. Eur J Vasc Endovasc Surg. 2011 Sep 42 Suppl 1 S1
Conroy S. End-of-life decisions in acute hospitals. Clin Med. 2011 Aug 11 4 436-43
Masala N, Walker A, Swanevelder J, Spyt TJ. Double orifice mitral valve causing severe regurgitation. Eur J Cardiothorac Surg. 2011 Nov 40 5 1269
Meta-analysis Global Group in Chronic Heart Failure (MAGGIC). Inc Squire IB The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: an individual patient data meta-analysis. Eur Heart J. 2011 Aug 6 Epub
Roland D, Haden S, Pryde K, Lachman P. Paediatric trainees and the quality improvement agenda: don't just do another audit. J R Soc Med. 2011 Aug 104 8 344-5
Angelakopoulou A et al (including Samani NJ). Comparative analysis of genome-wide-association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. Eur Heart J. 2011 Jul 30 Epub
Azevedo E, Castro P, Santos R, Freitas J, Coelho T, Rosengarten B, Panerai R. Autonomic dysfunction affects cerebral neurovascular coupling. Clin Auton Res. 2011 Dec 21 6 395-403
Haque R, Chong NW, Ali F, Chaurasia SS, Sengupta T, Chun E, Howell JC, Klein DC, Iuvone PM. Melatonin synthesis in retina: cAMP-dependent transcriptional regulation of chicken arylalkylamine N-acetyltransferase (Aanat) by a CRE-like sequence (CLS) and a TTATT repeat motif in the proximal promoter. J Neurochem. 2011 Oct 119 1 6-17
Coats TJ. Future research in emergency medicine: explanation or pragmatism? Large or small? Simple or complex? Emerg Med J. 2011 Dec 28 12 1004-7
Scott PA, Townsend PA, Ng LL, Zeb M, Harris S, Roderick PJ, Curzen NP, Morgan JM. Defining potential to benefit from implantable cardioverter defibrillator therapy: the role of biomarkers. Europace. 2011 Oct 13 10 1419-27
Ali D, Alzuwam A, McCann GP, Been M, Osman F. Giant cell myocarditis: an unusual presentation. Europace. 2011 Dec 13 12 1793-4
Galassi AR, Tomasello SD, Reifart N, Werner GS, Sianos G, Bonnier H, Sievert H, Ehladad S, Bufe A, Shofer J, Gershlick A, Hildick-Smith D, Escaned J, Erglis A, Sheiban I, Thuesen L, Serra A, Christiansen E, Buettner A, Costanzo L, Barrano G, Di Mario C. In-hospital outcomes of percutaneous coronary intervention in patients with chronic total occlusion: insights from the ERCTO (European Registry of Chronic Total Occlusion) registry. EuroIntervention. 2011 Aug 7 4 472-9
Hirota K, Lambert DG. Ketamine: new uses for an old drug? Br J Anaesth. 2011 Aug 107 2 123-6
van de Ven C, Bialecka M, Neijts R, Young T, Rowland JE, Stringer EJ, Van Rooijen C, Meijlink F, Nóvoa A, Freund JN, Mallo M, Beck F, Deschamps J. Concerted involvement of Cdx/Hox genes and Wnt signaling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zone. Development. 2011 Aug 138 16 3451-62
Veerabhadrappa P, Burger D, Carlberg B, Charchar F, Tomaszewski M, Harrap S; the New Investigators Committee, International Society of Hypertension. ISH Hypertension Future Leaders Group: a network for new investigators run by new investigators. J Hypertens. 2011 Aug 29 8 1664-1665
Turrell HE, Rodrigo GC, Norman RI, Dickens M, Standen NB. Phenylephrine preconditioning involves modulation of cardiac sarcolemmal K(ATP) current by PKC delta, AMPK and p38 MAPK. J Mol Cell Cardiol. 2011 Sep 51 3 370-80
Paul DS, Nisbet JP, Yang TP, Meacham S, Rendon A, Hautaviita K, Tallila J, White J, Tijssen MR, Sivapalaratnam S, Basart H, Trip MD; Cardiogenics Consortium; MuTHER Consortium, Göttgens B, Soranzo N, Ouwehand WH, Deloukas P. (inc Samani N and Goodall AH). Maps of open chromatin guide the functional follow-up of genome-wide association signals: application to hematological traits. PLoS Genet. 2011 Jun 7 6 e1002139
Bathula R, Hughes AD, Panerai RB, Potter JF, McG Thom SA, Tillin T, Shore AC, Hale R, Chambers J, Kooner J, Chaturvedi N. South Asians have adverse cerebrovascular haemodynamics, despite equivalent blood pressure, compared with Europeans. This is due to their greater hyperglycaemia. Int J Epidemiol. 2011 Dec 40 6 1490-8
Tuan J, Jeilan M, Kundu S, Nicolson W, Chung I, Stafford PJ, Ng GA. Regional fractionation and dominant frequency in persistent atrial fibrillation: effects of left atrial ablation and evidence of spatial relationship. Europace. 2011 Nov 13 11 1550-6
Tarpey P, Thomas S, Sarvananthan N, Mallya U, Lisgo S, Talbot CJ, Roberts EO, Awan M, Surendran M, McLean RJ, Reinecke RD, Langmann A, Lindner S, Koch M, Jain S, Woodruff G, Gale RP, Degg C, Droutsas K, Asproudis I, Zubcov AA, Pieh C, Veal CD, Machado RD, Backhouse OC, Baumber L, Constantinescu CS, Brodsky MC, Hunter DG, Hertle RW, Read RJ, Edkins S, O'Meara S, Parker A, Stevens C, Teague J, Wooster R, Futreal PA, Trembath RC, Stratton MR, Raymond FL, Gottlob I. Corrigendum: Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus. Nat Genet. 2011 Jun 28 43 7 720
Griffin SJ, Borch-Johnsen K, Davies MJ, Khunti K, Rutten GE, Sandbæk A, Sharp SJ, Simmons RK, van den Donk M, Wareham NJ, Lauritzen T. Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with type 2 diabetes detected by screening (ADDITION-Europe): a cluster-randomised trial. Lancet. 2011 Jul 9 378 9786 156-67
Tiruvoipati R, Botha J, Peek G. Effectiveness of extracorporeal membrane oxygenation when conventional ventilation fails: Valuable option or vague remedy? J Crit Care. 2011 Jun 22 Epub
Hardman JG, Lambert DG. Anaesthesia, critical care, and pain in the 21st century: the first decade. Br J Anaesth. 2011 Jul 107 1 1-2
Boyle JR, Thompson MM, Vallabhaneni SR, Bell RE, Brennan JA, Browne TF, Cheshire NJ, Hinchliffe RJ, Jenkins MP, Loftus IM, Macdonald S, McCarthy MJ, McWilliams RG, Morgan RA, Oshin OA, Pemberton RM, Pillay WR, Sayers RD. Pragmatic minimum reporting standards for endovascular abdominal aortic aneurysm repair. J Endovasc Ther. 2011 Jun 18 3 263-71
Aujla N, Davies MJ, Skinner TC, Gray LJ, Webb DR, Srinivasan B, Khunti K. The association between anxiety and measures of glycaemia in a population-based diabetes screening programme. Diabet Med. 2011 Jul 28 7 785-8
Rocca MA, Horsfield MA, Sala S, Copetti M, Valsasina P, Mesaros S, Martinelli V, Caputo D, Stosic-Opincal T, Drulovic J, Comi G, Filippi M. A multicenter assessment of cervical cord atrophy among MS clinical phenotypes. Neurology. 2011 Jun 14 76 24 2096-102
Naylor AR. What is the current status of invasive treatment of extracranial carotid artery disease? Stroke. 2011 Jul 42 7 2080-5
Gabbe BJ, Lyons RA, Lecky FE, Bouamra O, Woodford M, Coats TJ, Cameron PA. Comparison of mortality following hospitalisation for isolated head injury in England and wales, and victoria, australia. PLoS One. 2011 Jun 6 5 e20545
Dhillon OS, Narayan HK, Quinn PA, Squire IB, Davies JE, Ng LL. Interleukin 33 and ST2 in non-ST-elevation myocardial infarction: Comparison with Global Registry of Acute Coronary Events Risk Scoring and NT-proBNP. Am Heart J. 2011 Jun 161 6 1163-70
Crasto W, Jarvis J, Khunti K, Skinner TC, Gray LJ, Brela J, Troughton J, Daly H, Lawrence IG, McNally PG, Carey ME, Davies MJ. Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: The Microalbuminuria Education and Medication Optimisation (MEMO) study. Diabetes Res Clin Pract. 2011 Sep 93 3 328-36
Webb DR, Gray LJ, Khunti K, Srinivasan B, Taub N, Campbell S, Barnett J, Farooqi A, Echouffo-Tcheugui JB, Griffin SJ, Wareham NJ, Davies MJ. Screening for diabetes using an oral glucose tolerance test within a western multi-ethnic population identifies modifiable cardiovascular risk: the ADDITION-Leicester study. Diabetologia. 2011 Sep 54 9 2237-46
Weir RA, Clements S, Steedman T, Dargie HJ, McMurray JJ, Squire IB, Ng LL. Plasma TIMP-4 Predicts Left Ventricular Remodeling After Acute Myocardial Infarction. J Card Fail. 2011 Jun 17 6 465-71
Bradburn M, Goodacre SW, Fitzgerald P, Coats T, Gray A, Hassan T, Humphrey J, Kendall J, Smith J, Collinson P; On behalf of the RATPAC Research Team. Interhospital variation in the RATPAC Trial (Randomised Assessment of Treatment using Panel Assay of Cardiac markers). Emerg Med J. 2011 May 26 Epub
Conroy SP, Stevens T, Parker SG, Gladman JR. A systematic review of comprehensive geriatric assessment to improve outcomes for frail older people being rapidly discharged from acute hospital: 'interface geriatrics' Age Ageing. 2011 Jul 40 4 436-43
Dietis N, Rowbotham DJ, Lambert DG. Opioid receptor subtypes: fact or artifact? Br J Anaesth. 2011 Jul 107 1 8-18
Nelson CP, Rainbow RD, Brignell JL, Perry MD, Willets JM, Davies NW, Standen NB, Challiss RA. Principal role of adenylyl cyclase 6 in K+-channel regulation and vasodilator signalling in vascular smooth muscle cells. Cardiovasc Res. 2011 Sep 1 91 4 694-702
Wild PS et al (including Braund PS and Samani NJ). A Genome-wide Association Study Identifies LIPA as a Susceptibility Gene for Coronary Artery Disease. Circ Cardiovasc Genet. 2011 Aug 1 4 4 403-12
Brack KE, Coote JH, Ng GA. Vagus nerve stimulation protects against ventricular fibrillation independent of muscarinic receptor activation. Cardiovasc Res. 2011 Aug 1 91 3 437-46
Mohammad S, Gottlob I, Kumar A, Thomas M, Degg C, Sheth V, Proudlock FA. The Functional Significance of Foveal Abnormalities in Albinism Measured Using Spectral-Domain Optical Coherence Tomography. Ophthalmology. 2011 Aug 118 8 1645-52
Harwood RH, Goldberg SE, Whittamore KH, Russell C, Gladman JR, Jones RG, Porock D, Lewis SA, Bradshaw LE, Elliot RA; Medical Crises in Older People Study Group (MCOP). Collaborators: Schneider J, Conroy S, Avery A, Jurgens F, Edmans J, Gordon A, Robbins B, Dyas J, Logan P, Quinn C, Boardman H, Franklin M. Evaluation of a Medical and Mental Health Unit compared with standard care for older people whose emergency admission to an acute general hospital is complicated by concurrent 'confusion': a controlled clinical trial. Acronym: TEAM: Trial of an Elderly Acute care Medical and mental health unit. Trials. 2011 May 13 12 123
Yates T, Wilmot EG, Davies MJ, Gorely T, Edwardson C, Biddle S, Khunti K. Sedentary Behavior What's in a Definition? Am J Prev Med. 2011 Jun 40 6 e33-4
Kidher E, Krasopoulos G, Coats T, Charitou A, Magee P, Uppal R, Athanasiou T. The effect of prehospital time related variables on mortality following severe thoracic trauma. Injury. 2011 May 10 Epub
Kela R, Khunti K, Davies MJ. Liraglutide for type 2 diabetes mellitus. Expert Opin Biol Ther. 2011 Jul 11 7 951-9
Vogler M, Hamali HA, Sun XM, Bampton ET, Dinsdale D, Snowden RT, Dyer MJ, Goodall AH, Cohen GM. BCL2/BCL-XL-inhibition induces apoptosis, disrupts cellular calcium homeostasis and prevents platelet activation. Blood. 2011 Jun 30 117 26 7145-54
Winter J, Brack KE, Ng GA. The acute inotropic effects of cardiac contractility modulation (CCM) are associated with action potential duration shortening and mediated by β1-adrenoceptor signalling. J Mol Cell Cardiol. 2011 Aug 51 2 252-62
Brown CN, Hakim C, Sayers RD, London NJ, Nasim A. Is Use of a Continuous Autotransfusion System Beneficial in Emergency Abdominal Aortic Aneursym (AAA) Surgery? Ann Vasc Surg. 2011 May 25 4 481-4
Fuller G, Bouamra O, Woodford M, Jenks T, Patel H, Coats TJ, Oakley P, Mendelow AD, Pigott T, Hutchinson PJ, Lecky F. The Effect of Specialist Neurosciences Care on Outcome in Adult Severe Head Injury: A Cohort Study. J Neurosurg Anesthesiol. 2011 Jul 23 3 198-205
Naylor AR. Letter by Naylor regarding article, "Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack: a guideline for healthcare professionals from the american heart association/american stroke association". Stroke. 2011 Jun 42 6 e385
Thomas MG, Kumar A, Mohammad S, Proudlock FA, Engle EC, Andrews C, Chan WM, Thomas S, Gottlob I. Structural Grading of Foveal Hypoplasia Using Spectral-Domain Optical Coherence Tomography A Predictor of Visual Acuity? Ophthalmology. 2011 Aug 118 8 1653-60
Bankart MJ, Baker R, Rashid A, Habiba M, Banerjee J, Hsu R, Conroy S, Agarwal S, Wilson A. "Characteristics of general practices associated with emergency admission rates to hospital: a cross-sectional study." Emerg Med J. 2011 Jul 28 7 558-63
Fuller G, Bouamra O, Woodford M, Jenks T, Patel H, Coats TJ, Oakley P, Mendelow AD, Pigott T, Hutchinson PJ, Lecky F. Temporal trends in head injury outcomes from 2003 to 2009 in England and Wales. Br J Neurosurg. 2011 Jun 25 3 414-21
Buellesfeld L, Gerckens U, Schuler G, Bonan R, Kovac J, Serruys PW, Labinaz M, den Heijer P, Mullen M, Tymchak W, Windecker S, Mueller R, Grube E. 2-year follow-up of patients undergoing transcatheter aortic valve implantation using a self-expanding valve prosthesis. J Am Coll Cardiol. 2011 Apr 19 57 16 1650-7
CRASH-2 collaborators, Roberts I, Shakur H, Afolabi A, Brohi K, Coats T, Dewan Y, Gando S, Guyatt G, Hunt BJ, Morales C, Perel P, Prieto-Merino D, Woolley T. The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. Lancet. 2011 Mar 26 377 9771 1096-101
Stather P, Cheshire H, Bogwandas H, Peek G. Pneumothorax post paediatric chest drain removal. Thorac Cardiovasc Surg. 2011 Aug 59 5 302-4
Fuller G, Bouamra O, Woodford M, Jenks T, Stanworth S, Allard S, Coats TJ, Brohi K, Lecky F. Recent massive blood transfusion practice in England and Wales: view from a trauma registry. Emerg Med J. 2011 Mar 10 Epub
Guly HR, Bouamra O, Spiers M, Dark P, Coats T, Lecky FE; on behalf of the Trauma Audit and Research Network. Vital signs and estimated blood loss in patients with major trauma: Testing the validity of the ATLS classification of hypovolaemic shock. Resuscitation. 2011 May 82 5 556-559
Parker SG, Conroy S. Poor inpatient care for older people. BMJ. 2011 Feb 3 342 d373
Saeed NP, Horsfield MA, Panerai RB, Mistri AK, Robinson TG. Measurement of cerebral blood flow responses to the thigh cuff maneuver: a comparison of TCD with a novel MRI method. J Cereb Blood Flow Metab. 2011 May 31 5 1302-10
Vorwerk C, Coats TJ. Protocol driven sepsis management--time for a rethink? Emerg Med J. 2011 Jun 28 6 459-60
Vorwerk C, Manias K, Davies F, Coats TJ. Prediction of severe bacterial infection in children with an emergency department diagnosis of infection. Emerg Med J. 2011 Nov 28 11 948-51
Calo' G, Rizzi A, Cifani C, Di Bonaventura MV, Regoli D, Massi M, Salvadori S, Lambert DG, Guerrini R. UFP-112 a Potent and Long-Lasting Agonist Selective for the Nociceptin/Orphanin FQ Receptor. CNS Neurosci Ther. 2011 Jun 17 3 178-98
Lai VK, Galiñanes M. Protection of Human Myocardium by Bone Marrow Cells: Role of Long-Term Administration of the Mitochondrial K(ATP) Channel Opener Nicorandil. J Surg Res. 2011 Nov 171 1 66-70
Dunkley AJ, Davies MJ, Stone MA, Taub NA, Troughton J, Yates T, Khunti K. The Reversal Intervention for Metabolic Syndrome (TRIMS) study: rationale, design, and baseline data. Trials. 2011 12 107
Erridge C. Accumulation of Stimulants of Toll-Like Receptor (TLR)-2 and TLR4 in Meat Products Stored at 5 °C. J Food Sci. 2011 76 H72-9
Holman RR, Zinman B, Yusuf S, Sheridan PM, Anand SS, Bosch JJ, Conget I, Davies MJ, Pirags V, Pogue JM, Zimmet PZ, Gerstein HC. Incidence of Diabetes Following Ramipril or Rosiglitazone Withdrawal. Diabetes Care. 2011 Apr 22 Epub
Tambyraja AL, Fishwick NG, Bown MJ, Nasim A, McCarthy MJ, Sayers RD. Fenestrated Aortic Endografts for Juxtarenal Aortic Aneurysm: Medium Term Outcomes. Eur J Vasc Endovasc Surg. 2011 Apr 21 Epub
Winter J, Brack KE, Ng GA. Cardiac contractility modulation in the treatment of heart failure: initial results and unanswered questions. Eur J Heart Fail. 2011 Apr 21 Epub
Yates T, Wilmot EG, Khunti K, Biddle S, Gorely T, Davies MJ. Stand up for your health: Is it time to rethink the physical activity paradigm? Diabetes Res Clin Pract. 2011 Apr 18 Epub
Jilaihawi H, Chin D, Spyt T, Jeilan M, Vasa-Nicotera M, Mohamed N, Bence J, Logtens E, Kovac J. Comparison of Complete Versus Incomplete Stent Frame Expansion After Transcatheter Aortic Valve Implantation With Medtronic CoreValve Bioprosthesis. Am J Cardiol. 2011 Apr 18 Epub
Schwaeble WJ, Lynch NJ, Clark JE, Marber M, Samani NJ, Ali YM, Dudler T, Parent B, Lhotta K, Wallis R, Farrar CA, Sacks S, Lee H, Zhang M, Iwaki D, Takahashi M, Fujita T, Tedford CE, Stover CM. Targeting of mannan-binding lectin-associated serine protease-2 (Masp2) confers a significant degree of protection from myocardial and gastrointestinal ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 2011 Apr 18 Epub
Bor-Seng-Shu E, Oliveira MD, Panerai RB, Teixeira MJ. Predicting Symptomatic Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage. Neurosurgery. 2011 Apr 14 Epub
Bonow RO, Maurer G, Lee KL, Holly TA, Binkley PF, Desvigne-Nickens P, Drozdz J, Farsky PS, Feldman AM, Doenst T, Michler RE, Berman DS, Nicolau JC, Pellikka PA, Wrobel K, Alotti N, Asch FM, Favaloro LE, She L, Velazquez EJ, Jones RH, Panza JA; STICH Trial Investigators. Inc Spyt T Myocardial viability and survival in ischemic left ventricular dysfunction. N Engl J Med. 2011 364 1617-25
Velazquez EJ, Lee KL, Deja MA, Jain A, Sopko G, Marchenko A, Ali IS, Pohost G, Gradinac S, Abraham WT, Yii M, Prabhakaran D, Szwed H, Ferrazzi P, Petrie MC, O'Connor CM, Panchavinnin P, She L, Bonow RO, Rankin GR, Jones RH, Rouleau JL; STICH Investigators. Inc Spyt T Coronary-artery bypass surgery in patients with left ventricular dysfunction. N Engl J Med. 2011 364 1607-16
Villard E, Perret C, Gary F, Proust C, Dilanian G, Hengstenberg C, Ruppert V, Arbustini E, Wichter T, Germain M, Dubourg O, Tavazzi L, Aumont MC, Degroote P, Fauchier L, Trochu JN, Gibelin P, Aupetit JF, Stark K, Erdmann J, Hetzer R, Roberts AM, Barton PJ, Regitz-Zagrosek V; Cardiogenics Consortium, Aslam U, Duboscq-Bidot L, Meyborg M, Maisch B, Madeira H, Waldenström A, Galve E, Cleland JG, Dorent R, Roizes G, Zeller T, Blankenberg S, Goodall AH, Cook S, Tregouet DA, Tiret L, Isnard R, Komajda M, Charron P, Cambien F. A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy. Eur Heart J. 2011 Apr 1 Epub
Parthasarathy HK, Ménard J, White WB, Young WF Jr, Williams GH, Williams B, Ruilope LM, McInnes GT, Connell JM, Macdonald TM. A double-blind, randomized study comparing the antihypertensive effect of eplerenone and spironolactone in patients with hypertension and evidence of primary aldosteronism. J Hypertens. 2011 29 980-990
Tomasik T, Jozwiak J, Windak A, Rygiel K, Mastej M, Smithson WH, Mathers N, Tomaszewski M, Kaess BM, Tykarski A, Konduracka E, Grzeszczak W, Lukas W. Prevention of coronary heart disease in primary medical care in Poland: results from the LIPIDOGRAM study. Eur J Cardiovasc Prev Rehabil. 2011 18 287-96
Erridge C. Diet, commensals and the intestine as sources of pathogen-associated molecular patterns in atherosclerosis, type 2 diabetes and non-alcoholic fatty liver disease. Atherosclerosis. 2011 Feb 26 Epub
Bhandari SS, Davies JE, Struck J, Ng LL. Influence of confounding factors on plasma Mid-Regional pro-Adrenomedullin and Mid-Regional pro-A-type Natriuretic Peptide concentrations in healthy individuals. Biomarkers. 2011 16 281-7
Tomaszewski M, Charchar FJ, Nelson CP, Barnes T, Denniff M, Kaiser M, Debiec R, Christofidou P, Rafelt S, van der Harst P, Wang WY, Maric C, Zukowska-Szczechowska E, Samani NJ. Pathway Analysis Shows Association between FGFBP1 and Hypertension. J Am Soc Nephrol. 2011 22 947-55
Speliotes EK, Yerges-Armstrong LM, Wu J, Hernaez R, Kim LJ, Palmer CD, Gudnason V, Eiriksdottir G, Garcia ME, Launer LJ, Nalls MA, Clark JM, Mitchell BD, Shuldiner AR, Butler JL, Tomas M, Hoffmann U, Hwang SJ, Massaro JM, O'Donnell CJ, Sahani DV, Salomaa V, Schadt EE, Schwartz SM, Siscovick DS; NASH CRN; GIANT Consortium; MAGIC Investigators, Voight BF, Carr JJ, Feitosa MF, Harris TB, Fox CS, Smith AV, Kao WH, Hirschhorn JN, Borecki IB; GOLD Consortium. Inc Samani NJ. Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet. 2011 7 e1001324
Katsogridakis E, Dineen NE, Brodie FG, Robinson TG, Panerai RB. Signal-to-Noise Ratio of Bilateral Nonimaging Transcranial Doppler Recordings of the Middle Cerebral Artery is not Affected by Age and Sex. Ultrasound Med Biol. 2011 37 530-8
Klip IT, Voors AA, Anker SD, Hillege HL, Struck J, Squire I, van Veldhuisen DJ, Dickstein K; for the OPTIMAAL investigators. Prognostic value of mid-regional pro-adrenomedullin in patients with heart failure after an acute myocardial infarction. Heart. 2011 Mar 17 Epub
Panerai RB, Salinet AS, Brodie FG, Robinson TG. The influence of calculation method on estimates of cerebral critical closing pressure. Physiol Meas. 2011 32 467-82
McCann GP, Steadman CD, Ray SG, Newby DE; on behalf of the British Heart Valve Society. Managing the asymptomatic patient with severe aortic stenosis: randomised controlled trials of early surgery are overdue. Heart. 2011 Mar 12 Epub
Naylor AR, Bown MJ. Stroke after Cardiac Surgery and its Association with Asymptomatic Carotid Disease: An Updated Systematic Review and Meta-analysis. Eur J Vasc Endovasc Surg. 2011 Mar 9 Epub
Subudhi AW, Dimmen AC, Julian CG, Wilson MJ, Panerai RB, Roach RC. Effects of acetazolamide and dexamethasone on cerebral hemodynamics in hypoxia. J Appl Physiol. 2011 Mar 10 Epub
Schunkert H, König IR, Kathiresan S, Reilly MP, Assimes TL, Holm H, Preuss M, Stewart AF, Barbalic M, Gieger C, Absher D, Aherrahrou Z, Allayee H, Altshuler D, Anand SS, Andersen K, Anderson JL, Ardissino D, Ball SG, Balmforth AJ, Barnes TA, Becker DM, Becker LC, Berger K, Bis JC, Boekholdt SM, Boerwinkle E, Braund PS, Brown MJ, Burnett MS, Buysschaert I; Cardiogenics, Carlquist JF, Chen L, Cichon S, Codd V, Davies RW, Dedoussis G, Dehghan A, Demissie S, Devaney JM, Diemert P, Do R, Doering A, Eifert S, Mokhtari NE, Ellis SG, Elosua R, Engert JC, Epstein SE, de Faire U, Fischer M, Folsom AR, Freyer J, Gigante B, Girelli D, Gretarsdottir S, Gudnason V, Gulcher JR, Halperin E, Hammond N, Hazen SL, Hofman A, Horne BD, Illig T, Iribarren C, Jones GT, Jukema JW, Kaiser MA, Kaplan LM, Kastelein JJ, Khaw KT, Knowles JW, Kolovou G, Kong A, Laaksonen R, Lambrechts D, Leander K, Lettre G, Li M, Lieb W, Loley C, Lotery AJ, Mannucci PM, Maouche S, Martinelli N, McKeown PP, Meisinger C, Meitinger T, Melander O, Merlini PA, Mooser V, Morgan T, Mühleisen TW, Muhlestein JB, Münzel T, Musunuru K, Nahrstaedt J, Nelson CP, Nöthen MM, Olivieri O, Patel RS, Patterson CC, Peters A, Peyvandi F, Qu L, Quyyumi AA, Rader DJ, Rallidis LS, Rice C, Rosendaal FR, Rubin D, Salomaa V, Sampietro ML, Sandhu MS, Schadt E, Schäfer A, Schillert A, Schreiber S, Schrezenmeir J, Schwartz SM, Siscovick DS, Sivananthan M, Sivapalaratnam S, Smith A, Smith TB, Snoep JD, Soranzo N, Spertus JA, Stark K, Stirrups K, Stoll M, Tang WH, Tennstedt S, Thorgeirsson G, Thorleifsson G, Tomaszewski M, Uitterlinden AG, van Rij AM, Voight BF, Wareham NJ, Wells GA, Wichmann HE, Wild PS, Willenborg C, Witteman JC, Wright BJ, Ye S, Zeller T, Ziegler A, Cambien F, Goodall AH, Cupples LA, Quertermous T, März W, Hengstenberg C, Blankenberg S, Ouwehand WH, Hall AS, Deloukas P, Thompson JR, Stefansson K, Roberts R, Thorsteinsdottir U, O'Donnell CJ, McPherson R, Erdmann J; CARDIoGRAM Consortium, Samani NJ. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011 43 4 333-8
Coronary Artery Disease (C4D) Genetics Consortium. Peden JF, Hopewell JC, Saleheen D, Chambers JC, Hager J, Soranzo N, Collins R, Danesh J, Elliott P, Farrall M, Stirrups K, Zhang W, Hamsten A, Parish S, Lathrop M, Watkins H, Clarke R, Deloukas P, Kooner JS, Goel A, Ongen H, Strawbridge RJ, Heath S, Mälarstig A, Helgadottir A, Öhrvik J, Murtaza M, Potter S, Hunt SE, Delepine M, Jalilzadeh S, Axelsson T, Syvanen AC, Gwilliam R, Bumpstead S, Gray E, Edkins S, Folkersen L, Kyriakou T, Franco-Cereceda A, Gabrielsen A, Seedorf U, MuTHER Consortium, Eriksson P, Offer A, Bowman L, Sleight P, Armitage J, Peto R, Abecasis G, Ahmed N, Caulfield M, Donnelly P, Froguel P, Kooner AS, McCarthy MI, Samani NJ, Scott J, Sehmi J, Silveira A, Hellénius ML, van't Hooft FM, Olsson G, Rust S, Assman G, Barlera S, Tognoni G, Franzosi MG, Linksted P, Green FR, Rasheed A, Zaidi M, Shah N, Samuel M, Mallick NH, Azhar M, Zaman KS, Samad A, Ishaq M, Gardezi AR, Fazal-ur-Rehman M, Frossard PM, Spector T, Peltonen L, Nieminen MS, Sinisalo J, Salomaa V, Ripatti S, Bennett D, Leander K, Gigante B, de Faire U, Pietri S, Gori F, Marchioli R, Sivapalaratnam S, Kastelein JJ, Trip MD, Theodoraki EV, Dedoussis GV, Engert JC, Yusuf S, Anand SS. A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. Nat Genet. 2011 43 339-44
Fox ER, Young JH, Li Y, Dreisbach AW, Keating BJ, Musani SK, Liu K, Morrison AC, Ganesh S, Kutlar A, Ramachandran VS, Polak JF, Fabsitz RR, Dries DL, Farlow DN, Redline S, Adeyemo A, Hirschorn JN, Sun YV, Wyatt SB, Penman AD, Palmas W, Rotter JI, Townsend RR, Doumatey AP, Tayo BO, Mosley TH Jr, Lyon HN, Kang SJ, Rotimi CN, Cooper RS, Franceschini N, Curb JD, Martin LW, Eaton CB, Kardia SL, Taylor HA, Caulfield MJ, Ehret GB, Johnson T; The International Consortium for Blood Pressure Genome-wide Association Studies (ICBP-GWAS); CARDIoGRAM consortium; CKDGen consortium; KidneyGen consortium; EchoGen consortium; CHARGE-HF consortium, Chakravarti A, Zhu X, Levy D. Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet. 2011 Apr 8 Epub
Erridge C. Stimulants of Toll-like receptor (TLR)-2 and TLR-4 are abundant in certain minimally-processed vegetables. Food Chem Toxicol. 2011 Mar 3 Epub
Huzen J, Peeters W, de Boer RA, Moll FL, Wong LS, Codd V, de Kleijn DP, de Smet BJ, van Veldhuisen DJ, Samani NJ, van Gilst WH, Pasterkamp G, van der Harst P. Circulating Leukocyte and Carotid Atherosclerotic Plaque Telomere Length: Interrelation, Association With Plaque Characteristics, and Restenosis After Endarterectomy. Arterioscler Thromb Vasc Biol. 2011 Mar 3 Epub
Bradley DT, Badger SA, Bown MJ, Sayers RD, Hughes AE. Coding polymorphisms in the genes of the alternative complement pathway and abdominal aortic aneurysm. Int J Immunogenet. 2011 Feb 24 Epub
Verheugt FW, Steinhubl SR, Hamon M, Darius H, Steg PG, Valgimigli M, Marso SP, Rao SV, Gershlick AH, Lincoff AM, Mehran R, Stone GW. Incidence, prognostic impact, and influence of antithrombotic therapy on access and nonaccess site bleeding in percutaneous coronary intervention. JACC Cardiovasc Interv. 2011 4 191-7
Williams B. High blood pressure in young people and premature death. BMJ. 2011 342 d1104
Naylor AR. Invited commentary. J Vasc Surg. 2011 53 628
Salem MK, Butt HZ, Watts AP, Sayers RD, Bown MJ, Naylor AR. Spontaneous Cerebral Embolisation in Asymptomatic and Recently Symptomatic Patients with TIA/Minor Stroke. Eur J Vasc Endovasc Surg. 2011 Feb 16 Epub
Williams B, Lacy PS, Yan P, Hwee CN, Liang C, Ting CM. Development and validation of a novel method to derive central aortic systolic pressure from the radial pressure waveform using an N-point moving average method. J Am Coll Cardiol. 2011 57 951-61
C Reactive Protein Coronary Heart Disease Genetics Collaboration (CCGC), Wensley F, Gao P, Burgess S, Kaptoge S, Di Angelantonio E, Shah T, Engert JC, Clarke R, Davey-Smith G, Nordestgaard BG, Saleheen D, Samani NJ, Sandhu M, Anand S, Pepys MB, Smeeth L, Whittaker J, Casas JP, Thompson SG, Hingorani AD, Danesh J. Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BMJ. 2011 342 d548
Rainbow RD, Parker AM, Davies NW. Protein kinase C-independent inhibition of arterial smooth muscle K(+) channels by a diacylglycerol analogue. Br J Pharmacol. 2011 Feb 16 Epub
Davies M, Pratley R, Hammer M, Thomsen AB, Cuddihy R. Liraglutide improves treatment satisfaction in people with Type 2 diabetes compared with sitagliptin, each as an add on to metformin. Diabet Med. 2011 28 333-7
Narayan H, Dhillon OS, Quinn P, Struck J, Squire IB, Davies JE, Ng LL. C-Terminal Provasopressin (Copeptin) as Prognostic Marker after Acute Non ST Elevation Myocardial Infarction - Leicester Acute Myocardial Infarction Peptide II (LAMP II) study. Clin Sci (Lond). 2011 121 79-89
Edmondson AC, Braund PS, Stylianou IM, Khera AV, Nelson CP, Wolfe ML, Derohannessian SL, Keating BJ, Qu L, He J, Tobin MD, Tomaszewski M, Baumert J, Klopp N, Doering A, Thorand B, Li M, Reilly MP, Koenig W, Samani NJ, Rader DJ. Dense Genotyping of Candidate Gene Loci Identifies Variants Associated with High-Density Lipoprotein Cholesterol. Circ Cardiovasc Genet. 2011 Feb 8 Epub
Thomas MG, Crosier M, Lindsay S, Kumar A, Thomas S, Araki M, Talbot CJ, McLean RJ, Surendran M, Taylor K, Leroy BP, Moore AT, Hunter DG, Hertle RW, Tarpey P, Langmann A, Lindner S, Brandner M, Gottlob I. The clinical and molecular genetic features of idiopathic infantile periodic alternating nystagmus. Brain. 2011 134 892-902
Nielsen JC, Thomsen PE, Højberg S, Møller M, Vesterlund T, Dalsgaard D, Mortensen LS, Nielsen T, Asklund M, Friis EV, Christensen PD, Simonsen EH, Eriksen UH, Jensen GV, Svendsen JH, Toff WD, Healey JS, Andersen HR; on behalf of the DANPACE investigators. A comparison of single-lead atrial pacing with dual-chamber pacing in sick sinus syndrome. Eur Heart J. 2011 32 686-696
Clark AL, Johnson MJ, Squire I. Does home oxygen benefit people with chronic heart failure? BMJ. 2011 372 d234
Lappin DF, Sherrabeh S, Erridge C. Stimulants of Toll-like receptors 2 and 4 are elevated in saliva of periodontitis patients compared with healthy subjects. J Clin Periodontol. 2011 38 318-25
Kaess BM, Tomaszewski M, Braund PS, Stark K, Rafelt S, Fischer M, Hardwick R, Nelson CP, Debiec R, Huber F, Kremer W, Kalbitzer HR, Rose LM, Chasman DI, Hopewell J, Clarke R, Burton PR, Tobin MD, Hengstenberg C, Samani NJ. Large-Scale Candidate Gene Analysis of HDL Particle Features. PLoS One. 2011 6 e14529
Reinhard W, Kaess BM, Debiec R, Nelson CP, Stark K, Tobin MD, Macfarlane PW, Tomaszewski M, Samani NJ, Hengstenberg C. Heritability of Early Repolarization - A Population-Based Study. Circ Cardiovasc Genet. 2011 Jan 31 Epub
Dineen NE, Panerai RB, Brodie F, Robinson TG. Effects of ageing on cerebral haemodynamics assessed during respiratory manoeuvres. Age Ageing. 2011 40 199-204
Duckers HJ, Houtgraaf J, Hehrlein C, Schofer J, Waltenberger J, Gershlick A, Bartunek J, Nienaber C, Macaya C, Peters N, Smits P, Siminiak T, van Mieghem W, Legrand V, Serruys PW. Final results of a phase IIa, randomised, open-label trial to evaluate the percutaneous intramyocardial transplantation of autologous skeletal myoblasts in congestive heart failure patients: the SEISMIC trial. EuroIntervention. 2011 6 805-12
Naylor AR, Ricco JB. Just When We Thought We Knew All the Answers, Someone Changed the Questions! Eur J Vasc Endovasc Surg. 2011 41 150-2
Roberts I, Shakur H, Ker K, Coats T; CRASH-2 Trial collaborators. Antifibrinolytic drugs for acute traumatic injury. Cochrane Database Syst Rev. 2011 1 CD004896
Theologou T, Bashir M, Rengarajan A, Khan O, Spyt T, Richens D, Field M. Preoperative intra aortic balloon pumps in patients undergoing coronary artery bypass grafting. Cochrane Database Syst Rev. 2011 1 CD004472
Reilly MP, Li M, He J, Ferguson JF, Stylianou IM, Mehta NN, Burnett MS, Devaney JM, Knouff CW, Thompson JR, Horne BD, Stewart AF, Assimes TL, Wild PS, Allayee H, Nitschke PL, Patel RS; Myocardial Infarction Genetics Consortium; Wellcome Trust Case Control Consortium, Martinelli N, Girelli D, Quyyumi AA, Anderson JL, Erdmann J, Hall AS, Schunkert H, Quertermous T, Blankenberg S, Hazen SL, Roberts R, Kathiresan S, Samani NJ, Epstein SE, Rader DJ. Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. Lancet. 2011 377 383-92
Gabbe BJ, Biostat GD, Lecky FE, Bouamra O, Woodford M, Jenks T, Coats TJ, Cameron PA. The effect of an organized trauma system on mortality in major trauma involving serious head injury: a comparison of the United kingdom and victoria, australia. Ann Surg. 2011 253 138-43
Kumar A, Gottlob I, McLean RJ, Thomas S, Thomas M, Proudlock FA. Clinical and Oculomotor Characteristics of Albinism Compared to FRMD7 Associated Infantile Nystagmus. Invest Ophthalmol Vis Sci. 2011 52 2306-13
Stansby G, Mister R, Fowkes G, Roughton M, Nugara F, Brittenden J, Bradbury A, Ashley S, Shearman C, Hannon R, Flather M; Prospective Registry and Evaluation of Peripheral Arterial Risks, Events and Distribution Investigators. Stansby G, Bradbury A, Lowe G, Fowkes G, Flather M, Khan S, Mister R, Nugara F, Delahunty N, Flather M, Brittenden J, Cassar K, Varty K, Fisher C, Hannon RJ, McGuigan K, Bradbury AW, Burke E, Ashley S, Cosgrove C, Geroulakos G, Daskalopoulou S, Stansby G, Dugdill S, Gerrard D, King C, Earnshaw JJ, Parkin D, Blackett RL, Warren J, McCollum P, Bryce J, Osman IS, Jaipersad A, London NJ, Smith S, Gibbons CP, Boyce V, Curley PJ, Pannu A, Cleanthis M, Parvin SD, Baker S, Baker DM, Morris-Vincent P, Horrocks M, Parks A, Vohra RK, Lee C, Shearman CP, Williams J, Cheshire NJ, Allen L, Higman D, Bick C. High risk of peripheral arterial disease in the United Kingdom: 2-year results of a prospective registry. Angiology. 2011 62 111-8
Thomas MG, Kumar A, Kohl S, Proudlock FA, Gottlob I. High-Resolution In Vivo Imaging in Achromatopsia. Ophthalmology. 2011 Jan 6 Epub
Davies MJ, Kela R, Khunti K. Liraglutide - overview of the preclinical and clinical data and its role in the treatment of type 2 diabetes. Diabetes Obes Metab. 2011 13 207-20
West RM, Cattle BA, Bouyssie M, Squire I, de Belder M, Fox KA, Boyle R, McLenachan JM, Batin PD, Greenwood DC, Gale CP. Impact of hospital proportion and volume on primary percutaneous coronary intervention performance in England and Wales. Eur Heart J. 2011 32 706-11
Webb DR, Gray LJ, Khunti K, Campbell S, Dallosso H, Davies MJ. Contrasting cardiovascular risk profiles and prescribed cardio-protective therapies in newly-diagnosed type 2 diabetes identified through screening and standard practice. Diabetes Res Clin Pract. 2011 91 280-5
Lanktree MB, Guo Y, Murtaza M, Glessner JT, Bailey SD, Onland-Moret NC, Lettre G, Ongen H, Rajagopalan R, Johnson T, Shen H, Nelson CP, Klopp N, Baumert J, Padmanabhan S, Pankratz N, Pankow JS, Shah S, Taylor K, Barnard J, Peters BJ, Maloney CM, Lobmeyer MT, Stanton A, Zafarmand MH, Romaine SP, Mehta A, van Iperen EP, Gong Y, Price TS, Smith EN, Kim CE, Li YR, Asselbergs FW, Atwood LD, Bailey KM, Bhatt D, Bauer F, Behr ER, Bhangale T, Boer JM, Boehm BO, Bradfield JP, Brown M, Braund PS, Burton PR, Carty C, Chandrupatla HR, Chen W, Connell J, Dalgeorgou C, Boer A, Drenos F, Elbers CC, Fang JC, Fox CS, Frackelton EC, Fuchs B, Furlong CE, Gibson Q, Gieger C, Goel A, Grobbee DE, Hastie C, Howard PJ, Huang GH, Johnson WC, Li Q, Kleber ME, Klein BE, Klein R, Kooperberg C, Ky B, Lacroix A, Lanken P, Lathrop M, Li M, Marshall V, Melander O, Mentch FD, Meyer NJ, Monda KL, Montpetit A, Murugesan G, Nakayama K, Nondahl D, Onipinla A, Rafelt S, Newhouse SJ, Otieno FG, Patel SR, Putt ME, Rodriguez S, Safa RN, Sawyer DB, Schreiner PJ, Simpson C, Sivapalaratnam S, Srinivasan SR, Suver C, Swergold G, Sweitzer NK, Thomas KA, Thorand B, Timpson NJ, Tischfield S, Tobin M, Tomaszweski M, Verschuren WM, Wallace C, Winkelmann B, Zhang H, Zheng D, Zhang L, Zmuda JM, Clarke R, Balmforth AJ, Danesh J, Day IN, Schork NJ, de Bakker PI, Delles C, Duggan D, Hingorani AD, Hirschhorn JN, Hofker MH, Humphries SE, Kivimaki M, Lawlor DA, Kottke-Marchant K, Mega JL, Mitchell BD, Morrow DA, Palmen J, Redline S, Shields DC, Shuldiner AR, Sleiman PM, Smith GD, Farrall M, Jamshidi Y, Christiani DC, Casas JP, Hall AS, Doevendans PA, Christie JD, Berenson GS, Murray SS, Illig T, Dorn GW 2nd, Cappola TP, Boerwinkle E, Sever P, Rader DJ, Reilly MP, Caulfield M, Talmud PJ, Topol E, Engert JC, Wang K, Dominiczak A, Hamsten A, Curtis SP, Silverstein RL, Lange LA, Sabatine MS, Trip M, Saleheen D, Peden JF, Cruickshanks KJ, März W, O'Connell JR, Klungel OH, Wijmenga C, Maitland-van der Zee AH, Schadt EE, Johnson JA, Jarvik GP, Papanicolaou GJ; Hugh Watkins on behalf of PROCARDIS, Grant SF, Munroe PB, North KE, Samani NJ, Koenig W, Gaunt TR, Anand SS, van der Schouw YT; Meena Kumari on behalf of the Whitehall II Study and the WHII 50K Group, Soranzo N, Fitzgerald GA, Reiner A, Hegele RA, Hakonarson H, Keating BJ. Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet. 2011 88 6-18
The GoDARTS and UKPDS Diabetes Pharmacogenetics Study Group, Zhou K, Bellenguez C, Spencer CC, Bennett AJ, Coleman RL, Tavendale R, Hawley SA, Donnelly LA, Schofield C, Groves CJ, Burch L, Carr F, Strange A, Freeman C, Blackwell JM, Bramon E, Brown MA, Casas JP, Corvin A, Craddock N, Deloukas P, Dronov S, Duncanson A, Edkins S, Gray E, Hunt S, Jankowski J, Langford C, Markus HS, Mathew CG, Plomin R, Rautanen A, Sawcer SJ, Samani NJ, Trembath R, Viswanathan AC, Wood NW; MAGIC investigators, Harries LW, Hattersley AT, Doney AS, Colhoun H, Morris AD, Sutherland C, Hardie DG, Peltonen L, McCarthy MI, Holman RR, Palmer CN, Donnelly P, Pearson ER; The Wellcome Trust Case Control Consortium 2. Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet. 2011 43 117-120
Serrano-Gomez A, Thompson JP, Lambert DG. Nociceptin/orphanin FQ in inflammation and sepsis. Br J Anaesth. 2011 106 6-12
Salem MK, Sayers RD, Bown MJ, Eveson DJ, Robinson TG, Naylor AR. Rapid Access Carotid Endarterectomy can be Performed in the Hyperacute Period without a Significant Increase in Procedural Risks. Eur J Vasc Endovasc Surg. 2011 41 222-8
Malkawi AH, Resch TA, Bown MJ, Manning BJ, Poloniecki JD, Nordon IM, Loftus IM, Thompson MM, Hinchliffe RJ. Sizing Fenestrated Aortic Stent-grafts. Eur J Vasc Endovasc Surg. 2011 41 311-6
Roland D, Coats TJ. An early warning? Universal risk scoring in emergency medicine. Emerg Med J. 2011 28 263
Chacon M, Araya C, Panerai RB. Non-linear multivariate modeling of cerebral hemodynamics with autoregressive Support Vector Machines. Med Eng Phys. 2011 33 180-7
Mulla H, Hussain N, Tanna S, Lawson G, Manktelow BN, Tuleu C, Samani NJ, Pandya HC. Assessment of liquid captopril formulations used in children. Arch Dis Child. 2011 96 293-6
Rowlands RJ, Roland D. Antibiotics in childhood burns. Burns. 2011 37 359-60
Thomas SA, Friedmann E, Lee HJ, Son H, Morton PG; the HAT Investigators. Toff WD Changes in anxiety and depression over 2 years in medically stable patients after myocardial infarction and their spouses in the Home Automatic External Defibrillator Trial (HAT): a longitudinal observational study. Heart. 2011 97 371-81
Goodacre SW, Bradburn M, Cross E, Collinson P, Gray A, Hall AS; RATPAC Research Team. Coats TJ, et al The Randomised Assessment of Treatment using Panel Assay of Cardiac Markers (RATPAC) trial: a randomised controlled trial of point-of-care cardiac markers in the emergency department. Heart. 2011 97 190-6
Dawson JA, Choke E, Loftus IM, Cockerill GW, Thompson MM. A Randomised Placebo-controlled Double-blind Trial to Evaluate Lipid-lowering Pharmacotherapy on Proteolysis and Inflammation in Abdominal Aortic Aneurysms. Eur J Vasc Endovasc Surg. 2011 41 28-35
Gholap N, Davies M, Patel K, Sattar N, Khunti K. Type 2 diabetes and cardiovascular disease in South Asians. Prim Care Diabetes. 2011 5 45-56
Benhalima K, Wilmot E, Khunti K, Gray LJ, Lawrence I, Davies M. Type 2 diabetes in younger adults: Clinical characteristics, diabetes-related complications and management of risk factors. Prim Care Diabetes. 2011 5 57-62
Mainous AG 3rd, Everett CJ, Diaz VA, Baker R, Mangino M, Codd V, Samani NJ. Leukocyte telomere length and marital status among middle-aged adults. Age Ageing. 2011 40 73-8
Skinner TC, Carey ME, Cradock S, Dallosso HM, Daly H, Davies MJ, Doherty Y, Heller S, Khunti K, Oliver L. Comparison of illness representations dimensions and illness representation clusters in predicting outcomes in the first year following diagnosis of type 2 diabetes: Results from the DESMOND trial. Psychol Health. 2011 26 321-35
Lloyd GM, Neal CP, Arun C, London NJ, Hemingway DM. The prognostic value of circulating big endothelin-1 in patients undergoing potentially curative resection for colorectal cancer. Colorectal Dis. 2011 13 290-5
Robinson HJ, Samani NJ, Singh SJ. Can low risk cardiac patients be 'fast tracked' to Phase IV community exercise schemes for cardiac rehabilitation? A randomised controlled trial. Int J Cardiol. 2011 146 159-63
![[The University of Leicester]](unilogo.gif)


