Cardiovascular Cell Biology and Cell Signalling
| Section Leads: | Professor Nick Brindle, Professor David Lambert |
|---|---|
| Members: | Dr Clett Erridge, Professor Alison Goodall, Dr Karl E Herbert, Dr Rich Rainbow, Dr Glenn Rodrigo, Dr Jonathan P Thompson |
Members of this section have interests in:
- the variation in signalling mechanisms regulating vascular development, maintenance and regression - in particular the Tie family of receptor tyrosine kinases
- the pharmacology of nociceptin, opioid, vanilloid and urotensin receptors
- how traditional cardiovascular risk factors such as hypertension and diabetes promote mechanisms of human vascular cell injury and ageing, with particular emphasis on mitochondria
- the structure, function and regulation of cardiovascular potassium and calcium channels
- the effects of acute hyperglycaemia on cardiovascular ion channel regulation
- diurnal variations in ventricular function and arrhythmias; ischaemic preconditioning and remote conditioning of cardiac muscle
- inflammatory signalling pathways
- platelet biology and haemostasis.
