![[The University of Leicester]](unilogo.gif)
Dr Jonathan P Thompson
B.Sc., (First class Honours) in Medical Sciences, University of Leicester, 1986
M.B., Ch.B. University of Leicester, 1988
F.R.C.A 1994
M.D. University of Leicester, 2002
Tel: 0116 258 5291
Email: jt23@le.ac.uk
Address: Department of Cardiovascular Sciences, Clinical Division of Anaesthesia Critical Care & Pain Management,
University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, Leicester, LE1 5WW
For general enquiries, please email Shara McDonald or telephone 0116 258 5291
Research Interests
-
The role of urotensin II in hypertension, vascular disease, and in systemic sepsis
-
Studies of opioid receptors in human lymphocytes in ICU patients
-
The effect of stump catheterisation on pain after lower limb amputation
-
The use of cardiac troponin measurements as an indicator of myocardial damage in patients undergoing major vascular surgery
-
Evaluation of different methods of high frequency jet ventilation in a model of tracheal stenosis
External Positions
Assistant Editor, British Journal of Anaesthesia 2003-
Editorial Board Member of the R.C.A. CME Journal 'Continuing Education in Anaesthesia, Critical Care & Pain Management' 2001-
Honorary Secretary, Grants Officer and Member of Research Committee for the Vascular Anaesthesia Society of Great Britain and Ireland 2002-
Member of Council, Anaesthetic Research Society 2003-
Organiser of South Trent Primary and Final FRCA revision courses 1997-
Key Publications
Williams JP, Thompson JP, Young SP, Gold SJ, McDonald J, Rowbotham DJ, Lambert DG. Nociceptin and urotensin-II concentrations in critically ill patients with sepsis. Br J Anaesth. 2008 Jun 100 6 810-4
Camarda V, Spagnol M, Song W, Vergura R, Roth AL, Thompson JP, Rowbotham DJ, Guerrini R, Marzola E, Salvadori S, Cavanni P, Regoli D, Douglas SA, Lambert DG, Calò G. In vitro and in vivo pharmacological characterization of the novel UT receptor ligand [Pen5,DTrp7,Dab8]urotensin II(4-11) (UFP-803). Br J Pharmacol. 2006 Jan 147 1 92-100
Camarda V, Song W, Marzola E, Spagnol M, Guerrini R, Salvadori S, Regoli D, Thompson JP, Rowbotham DJ, Behm DJ, Douglas SA, Calo' G, Lambert DG. Urantide mimics urotensin-II induced calcium release in cells expressing recombinant UT receptors. Eur J Pharmacol. 2004 Sep 13 498 1-3 83-6
Thompson JP, Watt P, Sanghavi S, Strupish JW, Lambert DG. A comparison of cerebrospinal fluid and plasma urotensin II concentrations in normotensive and hypertensive patients undergoing urological surgery during spinal anesthesia: a pilot study. Anesth Analg. 2003 Nov 97 5 1501-3
Thompson JP, Hall AP, Russell J, Cagney B, Rowbotham DJ. The effect of remifentanil upon the haemodynamic response to orotracheal intubation. British Journal of Anaesthesia 1998 80 4 467-469
Boyle JR, Goodall S, Thompson JP, Bell PRF, Thompson MM. Endovascular AAA repair attenuates the inflammatory and renal responses associated with conventional surgery Journal of Endovascular Therapy 2000 7 5 359-371
Thompson JP, Rowbotham DJ Remifentanil – An opioid for the 21st century? Br J Anaesth. 1996 76 341-343
Williams JP, Thompson JP, McDonald J, Barnes TA, Cote T, Rowbotham DJ, Lambert DG Human Peripheral Blood Mononuclear Cells Express Nociceptin/Orphanin FQ But Not µ, d or k Opioid Receptors Anesthesia & Analgesia 2007 105 998 –1005
Thompson JP, Boyle JR, Thompson MM, Bell PRF, Smith G Cardiovascular and catecholamine responses during endovascular and conventional abdominal aortic aneurysm repair. European Journal of Vascular and Endovascular Surgery 1999 17 4 326-333
Boyle JR, Thompson JP, Thompson MM, Sayers RD, Smith G, Bell PRF Improved respiratory function and analgesia control after endovascular AAA repair Journal of Endovascular Surgery 1997 4 1 62-5
Links
Return to Cardiovascular Theme pages
