The mission of the Department of Cardiovascular Sciences is to undertake bench-to-bedside research, education and training, and clinical practice that impacts on the health and well-being of patients and the public.
Who We Are
The Department of Cardiovascular Sciences currently comprises around 124 staff and 73 postgraduate students. The Department has laboratory and clinical research facilities at Glenfield Hospital, the regional cardiac centre, including the £12.5M state-of-the-art University of Leicester British Heart Foundation Cardiovascular Research Centre, as well research facilities at the Leicester Royal Infirmary and the Henry Wellcome Building. The Department hosts two BHF-funded Chairs (Cardiology: Professor Nilesh Samani; Cardiac Surgery: Professor Gavin Murphy), and a National Institute of Health Research (NIHR) Biomedical Research Unit in Cardiovascular Disease. There are strong links with the University Hospitals of Leicester NHS Trust, where senior clinical academics provide leadership in patient care, as well as undergraduate and postgraduate medical teaching and training.
What We Do
Cardiovascular Research has been a strength of the Leicester Medical School since its inception. In the 2014 Research Excellence Framework, Cardiovascular Sciences contributed significantly to the University’s Clinical Medicine (UoA1) submission; over 70% of research was classified as internationally excellent (22% world leading), and 2 of the 4 submitted impact studies were cardiovascular and rated 4*. The work of the Department has contributed to major advances in the treatment of coronary heart disease, cardiac arrhythmias, heart failure, hypertension and stroke, and at a fundamental level improved our understanding of the causes, including genetic predisposition, to cardiovascular diseases. In addition, our expertise in genetics, novel biomarkers and clinical trials maps to Leicester Precision Medicine Institute.
The overarching strategy for cardiovascular research is based on two main principles: (i) to integrate high quality basic and clinical science research, and (ii) to focus on common cardiovascular diseases and on questions of direct clinical relevance and impact.
Research Team Structure
All academic staff and students in the Department of Cardiovascular Sciences are a member of at least one of the following Research Themes:
Within these themes, key areas of current research include:
- Arrhythmias and Cardiac Electrophysiology (GA Ng, Rainbow, Rodrigo, Toff)
- Biological ageing and cardiovascular diseases (Samani, Herbert, Codd)
- Cerebral Haemodynamics in Ageing and Stroke Medicine (Robinson, Panerai, Mistri, Haunton, Chung)
- Clinical studies in coronary and valvular heart disease (Gershlick, McCann, Kovac, Toff, Adlam)
- Genetics of coronary artery disease (Samani, Ye, Webb, Nelson, Stringer, Goodall)
- Imaging in cardiac and vascular disease (Robinson, Panerai, McCann, Chung, Levelt, Adlam)
- Novel approaches to cardiac and vascular protection (Murphy, Brindle, Lambert, Rodrigo, Rainbow)
- Novel biomarkers for prognostication in cardiovascular diseases (L Ng, Squire, Suzuki)
- Pathophysiology and management of aortic diseases (Bown, Suzuki, Sayers, Mariscalco, Saratzsis)
- Pathophysiology of rare coronary and valvular syndromes (Samani, Adlam, Bolger)