Dr Mark A Horsfield
BSc, (Aeronautical Engineering) 1982, University of Bristol
PhD, 1990, University of Cambridge
MIEE, Chartered Engineer
Tel: 0116 258 5080
Email: mah5@le.ac.uk
Address: Department of Cardiovascular Sciences, Medical Physics Department, Leicester Royal Infirmary, Leicester, LE1 5WW
For general enquiries, please email Miss Bharti Patel or telephone 0116 258 5626
Research Interests
Magnetic resonance imaging, with emphasis on:
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Diffusion-weighted MRI
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Perfusion/flow/vascular permeability imaging
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Multiple sclerosis
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Quantitative image analysis
Key Publications
Saeed NP, Horsfield MA, Panerai RB, Mistri AK, Robinson TG. Measurement of cerebral blood flow responses to the thigh cuff maneuver: a comparison of TCD with a novel MRI method. J Cereb Blood Flow Metab. 2011 May 31 5 1302-10
Horsfield MA, Sala S, Neema M, Absinta M, Bakshi A, Sormani MP, Rocca MA, Bakshi R, Filippi M. Rapid semi-automatic segmentation of the spinal cord from magnetic resonance images: Application in multiple sclerosis. Neuroimage. 2010 Apr 1 50 2 446-455
Horsfield MA, Thornton JS, Gill A, Jager HR, Priest AN, Morgan B. A functional form for injected MRI Gd-chelate contrast agent concentration incorporating recirculation, extravasation and excretion. Phys Med Biol. 2009 May 7 54 9 2933-49
Horsfield MA. MR image postprocessing for multiple sclerosis research. Neuroimaging Clin N Am. 2008 Nov 18 4 637-49
Bakshi R, Thompson AJ, Rocca MA, Pelletier D, Dousset V, Barkhof F, Inglese M, Guttmann CR, Horsfield MA, Filippi M. MRI in multiple sclerosis: current status and future prospects. Lancet Neurol. 2008 Jul 7 7 615-25
Horsfield MA, Bakshi R, Rovaris M, Rocca MA, Dandamudi VS, Valsasina P, Judica E, Lucchini F, Guttmann CR, Sormani MP, Filippi M. Incorporating domain knowledge into the fuzzy connectedness framework: application to brain lesion volume estimation in multiple sclerosis. IEEE Trans Med Imaging. 2007 Dec 26 12 1670-80
Pagani E, Horsfield MA, Rocca MA, Filippi M. Assessing atrophy of the major white matter fiber bundles of the brain from diffusion tensor MRI data. Magn Reson Med. 2007 Sep 58 3 527-34
Morgan B, Utting JF, Higginson A, Thomas AL, Steward WP, Horsfield MA. A simple, reproducible method for monitoring the treatment of tumours using dynamic contrast-enhanced MR imaging. Br J Cancer. 2006 May 22 94 10 1420-7
Jones DK, Catani M, Pierpaoli C, Reeves SJ, Shergill SS, O'Sullivan M, Maguire P, Horsfield MA, Simmons A, Williams SC, Howard RJ. A diffusion tensor magnetic resonance imaging study of frontal cortex connections in very-late-onset schizophrenia-like psychosis. Am J Geriatr Psychiatry. 2005 Dec 13 12 1092-9
Horsfield MA, Barker GJ, Barkhof F, Miller DH, Thompson AJ, Filippi M. Guidelines for using quantitative magnetization transfer magnetic resonance imaging for monitoring treatment of multiple sclerosis. J Magn Reson Imaging. 2003 Apr 17 4 389-97
Links
Magnetic Renansonce Imaging (MRI) Quantification
