Professor Irene Gottlob
Professor of Ophthalmology
Tel: 0116 258 6203
Email: ig15@le.ac.uk
Address: Cardiovascular Sciences, University of Leicester, Knighton Street Offices (Out-Patients), Leicester Royal Infirmary, Leicester, LE2 7LX
For general enquiries, please email the secretary, Mrs Sam Kerr or telephone 0116 258 6291
Research Interests
Her main areas of research are amblyopia, the regulation of eye movements and their disorders, in particular nystagmus, and the genetics of neuro-ophthalmic diseases. Professor Gottlob is the author of more than 120 peer reviewed research papers and book chapters. She is section editor of the British Journal of Ophthalmology and on the editorial board of other scientific journals. Professor Gottlob is an enthusiastic teacher of clinical and research students and trainees. She greatly enjoys teaching and has been named academic role model for students and trainees by the BMA.
Key Publications
Knapp CM, Gottlob I, McLean RJ, Rajabally YA, Abbott RJ, Rafelt S, Proudlock FA. Vertical optokinetic nystagmus in Parkinson's disease. Mov. Disord. 2009;24:1533-8.
Sarvananthan N, Surendran M, Roberts EO, Jain S, Shah N, Proudlock FA, Thompson JR, McLean RJ, Degg C, Woodruff G, Gottlob I. The prevalence of nystagmus: The Leicestershire nystagmus survey. Invest. Ophthalmol. Vis. Sci. 2009.
Thomas S, Proudlock FA, Sarvananthan N, Roberts EO, Awan M, McLean RJ, Surendran M, Kumar AS, Farooq SJ, Degg C, Gale RP, Reinecke RD, Woodruff G, Langmann A, Lindner S, Jain S, Tarpey P, Raymond FL, Gottlob I. Phenotypical characteristics of idiopathic infantile nystagmus with and without mutations in FRMD7. Brain. 2008;131:1259-67.
Farooq SJ, Gottlob I, Benskin S, Proudlock FA. The effect of aging on torsional optokinetic nystagmus. Invest. Ophthalmol. Vis. Sci. 2008; 49:589-93.
Knapp CM, Gottlob I, McLean RJ, Proudlock FA. Horizontal and vertical look and stare optokinetic nystagmus symmetry in healthy adult volunteers. Invest. Ophthalmol. Vis. Sci. 2008; Feb;49(2):581-8;(3.3766).
Pieh C, Simonsz-Toth B, Gottlob I. Nystagmus characteristics in congenital stationary night blindness (CSNB). Br. J. Ophthalmol. 2008;Feb:92(2):236-40.
McLean RJ, Proudlock FA, Thomas S, Degg C, Gottlob I. 'Congenital nystagmus: randomized, controlled, double-masked trial of memantine/gabapentin.' Ann. Neurol. 2007 Feb;61(2):130-8.
Tarpey P, Thomas S, Sarvananthan N, Mallya U, Lisgo S, Talbot CJ, Roberts EO, Awan M, Surendran M, McLean RJ, Reinecke RD, Langmann A, Lindner S, Koch M, Jain S, Woodruff G, Gale RP, Degg C, Droutsas K, Asproudis I, Zubcov AA, Pieh C, Veal CD, Machado RD, Backhouse OC, Baumber L, Constantinescu CS, Brodsky MC, Hunter DG, Hertle RW, Read RJM, Edkins S, O'Meara S, Parker A, Stevens C, Teague J, Wooster R, Futreal PA, Trembath RC, Stratton MR, Raymond FL, Gottlob I. 'Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus'. Nat. Genet. 2006 Nov;38(11):1242-4.
Proudlock FA, Khanna A, Gottlob I. Filling-in along horizontal and vertical meridian. Invest. Ophthalmol. Vis. Sci. 2006; 47:453-60.
Sabri K, Knapp CM, Thompson JR, Gottlob I. The VF-14 and psychological impact of amblyopia and strabismus. Invest Ophtalmol Vis Sci 2006; 47; 4386-92.
