Matt Bown
Senior Lecturer in Surgery
MB BCh - University of Wales College of Medicine - 1997
MD - University of Leicester - 2003
FRCS - The Royal College of Surgeons of England - 2008
PGCert (Bioinformatics) - Oxford University - 2009
Telephone: 0116 252 3299 Email: m.bown@le.ac.uk
Address: Department of Cardiovascular Sciences, University of Leicester, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, Leicester, LE2 7LX
Research Interests
I was initially appointed as a Clinical Lecturer in 2003 and, following the award of my CCT and a HEFCE Clinical Senior Lecturer Fellowship, was appointed as a Senior Lecturer in 2010. During my time with the department I have been involved in a continuing research programme investigating the pathogenesis of abdominal aortic aneurysms (AAA) and, more recently, have developed an interest into the causes of atherosclerotic plaque instability. The majority of my research involves the application of post-genomic experimental approaches to these subject areas. I also have an interest in evidence synthesis. I am currently leading a worldwide collaboration 'The Aneurysm Consortium' which was formed for the purposes of conducting a genome-wide association study of AAA, funded by The Wellcome Trust, and the results from this study are expected to be available in 2011.
Funding Sources
Key Publications
Bown MJ, Bolia A, Sutton AJ. Subintimal Angioplasty: Meta-analytical Evidence of Clinical Utility. Eur J Vasc Endovasc Surg. 2009 Sep 38 3 323-37
Rayt HS, Sutton AJ, London NJ, Sayers RD, Bown MJ. A Systematic Review and Meta-analysis of Endovascular Repair (EVAR) for Ruptured Abdominal Aortic Aneurysm. Eur J Vasc Endovasc Surg. 2008 Nov 36 5 536-44
Bown MJ, Braund PS, Thompson JR, London NJL, Samani NJ, Sayers RD. Association Between the Coronary Artery Disease Risk Locus on Chromosome 9p21.3 and Abdominal Aortic Aneurysm. Circ Cardiovasc Genet 2008 Oct 1 1 39-42
Franks SC, Sutton AJ, Bown MJ, Sayers RD. Systematic review and meta-analysis of 12 years of endovascular abdominal aortic aneurysm repair. Eur J Vasc Endovasc Surg. 2007 Feb 33 2 154-71
Bown MJ, Burton PR, Horsburgh T, Nicholson ML, Bell PR, Sayers RD. The role of cytokine gene polymorphisms in the pathogenesis of abdominal aortic aneurysms: a case-control study. J Vasc Surg. 2003 May 37 5 999-1005
Bown MJ, Sutton AJ, Bell PR, Sayers RD. A meta-analysis of 50 years of ruptured abdominal aortic aneurysm repair. Br J Surg. 2002 Jun 89 6 714-30
Links
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