Direct Contact Details:

Tel: 0116 229 7058

Email: ss115@le.ac.uk

Career

• Degree: Biochemistry BA, University of Oxford (1991)

• Postgraduate Research Assistant in the laboratory of Professor Ann Harris,Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford (1991-1993)

• DPhil: University of Oxford (1996)

• Postdoctoral Research Assistant in the laboratory of Professor Jean-Louis Carpentier, Department of Morphology, University of Geneva, Switzerland (1996-1998)

• Postdoctoral Research Fellow in the laboratory of Professor Richard Trembath,

• Department of Genetics, University of Leicester (1998-2005)

• Research Councils UK Research Fellow, Department of Biochemistry, University of Leicester (2005-)

Research Interests

• The nuclear envelope:
• Understanding the mechanism of fat-loss in partial lipodystrophy, in particular focusing on the potential role of lamin A interaction with the adipocyte differentiation factor, SREBP1.
• Understanding the role of ZMPSTE24 and pre-lamin A processing in disease causation.
• Characterisation of the SUN domain family of proteins and their role in nuclear positioning and migration.

Link to: Susan Shackleton's Research page