NEWS
- PhD studentship available to work with Dr Peter Moody, Professor Emma Raven(Chemistry) and Dr Matthew Blakely (Institut Laue-Langevin,
Grenoble) on the structure of heme enzyme intermediates using neutron crystallography, see link - BBSRC 2011 Responsive Mode Grant, circa £316,000, awarded to Prof Geerten Vuister - "Validation of biomacromolecular structures determined by NMR spectroscopy and deposited in the Protein Data Bank"
- BBSRC 2011 Responsive Mode Grant, circa £550,000, awarded to Dr Shaun Cowley and Prof John Schwabe - "Understanding the recruitment of Class I HDACs into diverse repression complexes: implications for physiological activity and therapeutic development"
- Biochemistry PhD Student (Alice Barkell) wins UCB Celltech meeting poster prize
- Wellcome Trust Equipment Award - Dr P C E Moody, Professor's John Schwabe and Emma Raven (Chemistry)
- New approach could have a major impact on antibody engineering
- Department of Biochemistry 50th Anniversary
- Archived News

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- Info
Publications
- Carrera S, de Verdier PJ, Khan Z, Zhao B, Mahale A, Bowman KJ, Zainol M, Jones GD, Lee SW, Aaronson SA, Macip S. Protection of cells in physiological oxygen tensions against DNA damage-induced apoptosis. J Biol Chem. 2010 Apr 30;285(18):13658-65. Epub 2010 Mar 12.
- Muñoz-Fontela C, Macip S, Martínez-Sobrido L, Brown L, Ashour J, García-Sastre A, Lee SW, Aaronson SA. Transcriptional role of p53 in interferon-mediated antiviral immunity. J Exp Med. 2008 Aug 4;205(8):1929-38.
- Tan MC, Battini L, Tuyama AC, Macip S, Melendi GA, Horga, MA. Characterization of human metapneumovirus infection of myeloid dendritic cells. Virology. 2007 Jan 5;357(1):1-9.
- Battini L, Fedorova E, Macip S, Li X, Wilson PD, Gusella GL. Stable knockdown of polycystin-1 confers integrin-alpha2beta1-mediated anoikis resistance. J Am Soc Nephrol. 2006 Nov;17(11):3049-58.
- Macip S, Kosoy A, Lee SW, O'Connell MJ, Aaronson SA. Role of a Chk1-dependent G2 checkpoint in protecting p53-null cancer cells from oxidative stress. Oncogene, 2006 (25): 6037-6047.
- Horga MA, Macip S, Tuyama AC, Tan MC, Gusell GL. Human parainfluenza virus 3 neuraminidase activity contributes to dendritic cell maturation. Viral Immunol. 2005;18(3):523-33.
- Ongusaha, PP, Kwak JC, Zwible AJ, Macip S, Higashiyama S, Taniguchi N, Fang L, Lee SW. HB-EGF is a potent inducer of tumor growth and angiogenesis. Cancer Res. 2004 Aug 1;64(15):5283-90.
- Ohtsuka T, Ryu H, Minamishima YA, Macip S, Sagara J, Aaronson SA, Lee SW. ASC functions as an adaptor for Bax and regulates a p53-Bax mitochondrial pathway of apoptosis. Nat Cell Biol. 2004 Feb;6(2):121-8. Epub 2004 Jan 18.
- Macip S, Igarashi M, Berggren P, Lee SW, Aaronson SA. Influence of induced ROS levels in determining p53-mediated growth arrest or apoptosis. Mol Cell Biol, 23(23):8576-85, 2003
- Macip S, Igarashi M, Fang L, Chen A, Pan ZQ, Lee SW, Aaronson SA. Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence. EMBO Journal, 21(9):2180-88, 2002
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Department of Biochemistry Henry Wellcome Building Lancaster Road Leicester LE1 9HN
T: +44(0)116 229 7038 F: +44(0)116 229 7018 biochemistry@le.ac.uk
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