Geneta:Gene Targeting and Transgenic Service

The ‘Embryonic Stem Cell Facility’ was established in 1997 with support from the Wellcome Trust, but is now run on a self-supporting basis through contract generated income. The facility comprises a tissue culture suite with state-of-the-art equipment for culturing mouse embryonic stem cells and for generating ES cell lines with targeted genetic mutations. Working closely with the Transgenic Mouse Unit within the Division of Biomedical Services, the facility generates mouse lines containing specific genetic mutations from the targeted ES cells. The facility has an international reputation in the generation of knockout mice, with a particular strength in the generation of knockouts for mouse genes involved in cell signaling and cell adhesion. Building on the success of transgenic technology established at Leicester, and following the move to brand new facilities in the Henry Wellcome Building, the service has now been launched as Geneta to external as well as internal researchers.

Click here to visit the Geneta web site