Electron Microscopy Facility

EM Lab equipment montage

Welcome

Electron microscopes, whether of the transmission (TEM) or the scanning (SEM) type, relate to the  study of specimen ultrastructure at levels of resolution that transcend the modest possibilities attainable using light microscopes.  Additionally, for many specimens the superior depth of field achieved using a scanning electron microscope makes it the instrument of choice, even at quite low magnifications.

The facility is located on the lower ground  floor of the Adrian Building (Office: LG27).  The facilities and services are available to academic, research staff and students (graduate and undergraduate). Work for customers external to the University is also undertaken and new clients are always welcome.

We are accustomed to tackling routine problems with specimens ranging from the microbiological to the geological.  Particular expertise is present in a number of areas such as high resolution metal shadowing of particulate specimens including macromolecules,  cryo-ultramicrotomy (ultrathin sectioning of frozen specimens) and other procedures such as immunolabelling of specific sites within tissues.  The Director and the staff are always happy to discuss either brief ‘service’ or longer collaborative arrangements.  Please ask us for a copy of our current charging rates outlining the costs and basis upon which work can be undertaken.  The Laboratory resources are also available for use in connection with other projects external to the College where an appropriate charge will be made.  Commercial work is charged at  pre-negotiated rates.

Equipment

We have two transmission electron microscopes, one with digital image acquisition, capable of resolution at the 0.3nm level and a PC controlled SEM.  Specimen preparation for TEM is supported by several ultramicrotomes, one of which supports cryo work and a range of vacuum coating units for macromolecular work.  For SEM we have critical point drying and sputter coating equipment.

User groups

The Laboratory is primarily a research facility used by senior researchers, postdoctoral scientists and postgraduate students.  The facility is also used by final year undergraduate project students.  For in-experienced users and students, training is available.

Project initiation

Please contact the Director or laboratory staff to arrange a discussion.  We have expertise available amongst our user base as well as ‘in house’ and we will be happy to explore how your problems can best be tackled.

 

Services

 

Contacts

emlab@le.ac.uk Tel: +44 (0)116 252 3370

 

University of Leicester Microscopy Home Page

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